Brookhaven Hospital: Mental Health Treatment for Behavioral Health Problems, Chemical Dependency, Eating Disorders, Brain Injuries, and Renewal Christian Treatment and Recovery

Tuesday, February 05, 2008 9:20 AM
posted by Rolf B. Gainer, Ph.D.

Brain Function in Borderline Personality Disorder

The cause of Borderline Personality Disorder has challenged researchers and clinicians for years. The hallmarks of Borderline Personality Disorder: a characteristic negative affective state; high reactivity and diminished ability to self-regulate emotion in previous neuropsychological studies have been attributed to orbitofrontal dysfunction. A study by Silbersweig et al published in the American Journal of Psychiatry 2007 December; 164: 1832 involving 16 individuals with Borderline Personality Disorder and 14 control subjects showed less activation of the subgenual anterior cingulate cortex and the posterior medial orbitofrontal cortex than the controls did and more activity in the left and right extended amygdala and ventral striatum. This study is important in helping individuals with Borderline Personality Disorder with more specific pharmacological interventions and in using more targeted approaches to help individuals learn to self-regulate their behavior.

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Rolf B. Gainer, Ph.D., Diplomate ABDA, is the Chief Executive Office at Brookhaven Hospital and the Vice President of Rehabilitation Institutes of America. Dr. Gainer has been involved in the design and operation of treatment programs since 1977.

Stephen Harnish, MD is the Medical Director of Brookhaven Hospital. Dr. Harnish is a member of the American Psychiatric Association and is well known in Oklahoma for his informative radio and television appearances.

Aric Thorpe, MHR, is Brookhaven Hospital's Pastoral Liaison Representative. He conducts the quarterly Minister's Lifeline series and provides mental health information to pastors and clergy.

Sarah McGee, BA, serves as the Community Education Provider for Brookhaven Hospital. She provides information on mental health and drug and alcohol treatment to healthcare professionals in Oklahoma and surrounding states.

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