SSRIs during pregnancy may lead to problems

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Findings from a study published in the October issue of Archives of Pediatrics and Adolescent Medicine have indicated that SSRI (selective serotonin re-uptake inhibitor) use during pregnancy may lead to issues for developing babies. According to the study, SSRI therapy during pregnancy could cause adverse neonatal outcomes in that those that took antidepressants among the population studied were more likely have a five-minute Apgar score of 7 or less (OR 4.44, 95% CI 2.58 to 7.63) and to be admitted to the NICU (OR 2.39, 95% CI 1.69 to 3.39). According to Najaaraq Lund, MD, of Aarhus University in Denmark and the Bandim Health Project in Bissau, Guinea-Bissau, and colleagues, “The study justifies increased awareness to the possible effects of intrauterine exposure to antidepressant… however, treatment of depression during pregnancy may be warranted and future studies need to distinguish between individual SSRIs to find the safest medication.” Click here to read an article from US News and World Report that discusses this study more.

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